Pioneering Early Phase Trials: PROs and Dose Optimization
Expert Prof. Christophe Massard explains that phase I oncology trials must now integrate dose optimization, toxicity assessment with structured PROs to inform the optimal dose for later phases. Discover the key role of RPM and digital tools in this process.
Dec 4, 2025
3 minutes
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Watch Prof. Christophe Massard, Medical Oncologist and Head of DITEP at Gustave Roussy, discuss the crucial evolution of early-phase oncology trials. He explains why defining safety requires dose optimization, integrating acute/chronic toxicity assessment with Patient-Reported Outcomes (PROs). Learn how Remote Patient Monitoring (RPM) and digital tools capture high-frequency, structured data to accelerate this path from Phase I to drug approval.

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